Hello,
Just wanted to share my experience with sodium butyrate, I’ve taken this supplement since three weeks and recently I’ve seen improvement in libido.
@secondlife How long do you recommend taking it ?
take care
Hi @philippe
Sodium Butyrate can exert some epigenetic effects very rapidly. Even a few hours of exposure can result in H4 histone hyperacetylation. [1] This effect can persist beyond withdrawal however chronic exposure is required to exert more stable long term epigenetic changes, particularly in the context of its neurogenic effects. In a study of cerebral ischemia, 14 days of treatment with sodium butyrate enhanced markers of neurogenesis in the frontal cortex, whilst only 7 days did not. [2] This was a function of Butyrate maintaining H3 acetylation, which was lost in the control group not exposed to Butyrate.
[1] https://pubmed.ncbi.nlm.nih.gov/10716680/
[2] https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1471-4159.2009.06212.x