Read through my latest articles on Post-Accutane Syndrome.
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Gut and Microbiome
PPAR: The Link Between The Gut, Allopregnanolone And The Brain
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors to regulate metabolic health. There are three types of PPARs: alpha, gamma and delta. When bound to by fatty acids (such as prostaglandins) influence processes such as fat burning, lipid storage and glucose metabolism. [1] Among the long list of side effects of Accutane, at the top of the list of immediate concern is…
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Repairing the Gut After Accutane With Butyrate
Introduction Butyrate is a short chain fatty acid, which is endogenously produced through microbial fermentation of dietary fibres in the lower intestinal tract. Short chain fatty acids (SCFAs) such as acetate, propionate and butyrate are produced by the bacteria in the colon from starch and dietary fibres. Some fermented foods contain very small quantities naturally, such as Parmesan or pecorino cheeses, and anyone familiar with the supplement Sodium Butyrate will…
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How Accutane Changes Your Gut
Introduction The gut is the colloquial term for the gastrointestinal tract, the long winding system of the intestines that’s responsible for the absorption of nutrients and the eventual expulsion of waste. Whilst there may not be an immediately obvious connection between the gut and brain health, the two systems are in fact deeply intertwined. The term “gut-brain axis” has become increasingly popularised. The relationship between the two organs is a…
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