Read through my latest articles on Post-Accutane Syndrome.
Navigate Topics
Hormones
Quick Read: Can Accutane damage your testicles?
Introduction It’s widely recognised that hormones play an important role in the develop of acne. It’s no coincidence that acne is most prevalent during the teenagehood, where the body rapidly develops under the sudden flood of hormones released from the sex organs (testes or ovaries) as well as the pituitary gland. These hormones play a vital role in guiding the body to develop key secondary sexual characteristics, such as broad…
Keep reading
How Accutane Changes Your Hormones
Introduction As it currently stands, there are only two known ways to influence acne: interventions involving PPARs (a set of hormone receptors involved in fatty acid metabolism) and hormonal interventions. It’s no coincidence that acne occurrence is most frequent during the hormone-saturated years of adolescence. It, therefore, shouldn’t be surprising that Accutane treatment can cause radical changes in the hormonal profile, particularly affecting androgens. Androgens are typically male hormones, such…
Keep reading
How Accutane Changes The Androgen Receptor
Introduction Androgen signalling plays a crucial role in the development of acne, influenced not just by hormonal levels but also variations in the androgen receptor (AR) gene. Androgens like Testosterone and DHT plainly exacerbate acne, and while isotretinoin has been shown to alter serum hormone levels, this effect is typically minor and transient. However, this doesn’t mean that Androgenic signalling isn’t involved in Accutane’s therapeutic effects. The AR’s influence on…
Keep reading